Tailored treatment for ALS poised to move ahead | Nature Medicine | Carrie ArnoldThe US Food and Drug Administration (FDA) has provisionally approved an experimental personalized treatment for a young woman with ALS. The therapy, known as an antisense oligonucleotide (ASO), is designed to disable mutated strands of genetic code to prevent them from producing a protein that causes neurological damage. Click here for the full article
Study Adds to Evidence that Smoking Increases Risk for ALS | ALS News Today | Jose Marques LopesCigarette smoking has been proposed as a risk factor for developing ALS and accelerating disease progression. However, methodological concerns hamper definitive conclusions of whether smoking causes the disease. Click here for the full article.
Shocking: New Zealand death rate for motor neuron disease five times global average | Hawthorne Caller | Mike BillingsThe Global Burden of Disease (GBD) study – the world‘s largest scientific effort to qualify the health loss from more than 300 major diseases, injuries and risk factors – found the mortality rate for MND in New Zealand was as high as 2.2 deaths per 100,000 people. Click here for the full article.
Swim training improves muscle strength in mouse model of ALS | ALS News Today | Joana CarvalhoSwim training reduced the loss of muscle strength associated with ALS (5% less between 11 and 15 weeks), and increased citrate synthase activity by 26% compared with ALS mice that did not undergo swim training. Click here for the full article.
ALS Researchers Discover New Biomarker and Drug Target | GENA research team led by scientists at Harvard University said it has found a potential new biomarker and drug target for ALS. Published in Nature Neuroscience, the study relied on stem cell models of human motor neurons to reveal the gene STMN2 as a potential therapeutic target. Click here for the full article.
Major breakthrough in MND drug trial | MercuryAustralian scientists have developed a groundbreaking drug which postpones the development of Motor Neuron Disease. After a six-month drug trial, researchers at the Florey Institute and the University of Melbourne claim the drug CuATSM has slowed progress of the disease by 70 per cent in 32 patients. Click here for the full article and video.
New Aussie drug gives hope to treat MND | SBS NEWSAustralian researchers have developed a drug called CuATSM which has been found to slow the progression of motor neurone disease. Click here for the full article.
New Zealand has highest motor neurone mortality rate in the world | Stuff | Hannah MartinNew Zealand has the highest mortality rates for motor neurone diseases in the world, new research has found. But little is known about why — sounding alarm bells for experts. Click here for full article
New Zealand has world’s highest death rate from motor neuron disease | News Hub | Jamie EnsorA global study has revealed NZ has the highest mortality rate from MND, with 2 kiwis dying from the disease each week. According to the study, the risk of developing the disease is 1 in 300. Click here for the full article
Shocking:New Zealand death rate for motor neuron disease five times global average | NZ Herald | Emma Russell
NZ's MND death rate is the highest in the world and five times the global average, a new study has found. Experts are warning this shocking new finding should be a major wake-up call. Click here for full article
Study reveals shocking death rates for Kiwis with motor neurone disease | NZ HeraldDr Emma Scotter, who led the study, said NZ doesn't have higher MND mortality rates just due to living longer, or having a greater proportion of older people in our population. "It's something other than just an age effect," Scotter said. Click here for the full article
NZ has highest rate of motor neurone disease of any country in the world | 1 News NowA new study has found NZ has the highest rate of MND of any country in the world. Auckland Uni scientists found the MND mortality rate is as high as 2.8 deaths per 100,000 people. Internationally, the average is just 1.67 deaths per 100,000 people. Click here for full article and video clip
Study: Athletes and footballers may be at greater risk of disease which killed Celtic legend Jimmy Johnstone | Herald Scotland | V.WeldonIntense exercise could increase the risk of developing motor neurone disease (MND), research suggests. People who are the most physically active, such athletes and footballers, could be as much as 26 per cent more likely to go on to suffer from the devastating condition. Click here for the full article
Scientists discover mechanism behind motor neurone disease | BBC News
Scientists say they have made a breakthrough in understanding the cause of both motor neurone disease and a rare form of dementia. They have discovered what causes a protein called FUS to stay in a jelly-like state, killing off brain cells.Click here for the full article