MND in the News

FDA Approves New Treatment Option for Patients with ALS

After a long road filled with scrutiny and uncertainty, Amylyx’s amyotrophic lateral sclerosis (ALS) drug,…Read More

Extended clinical trial for drug Tofersen shows promise in slowing MND progression

A Phase 3 clinical trial of the investigational drug tofersen in patients with MND caused…Read More

A new study reports that abnormalities in the SOD1 protein are also a common factor in sporadic MND.

Interesting findings from Kay Double and Benjamin Trist at the University of Sydney – the…Read More

FDA Accepts Biogen’s New Drug Application and Grants Priority Review of Tofersen for SOD1 MND

Biogen is seeking approval of tofersen under the FDA’s accelerated approval pathway, based on the…Read More

AMX0035 approved by Health Canada

Albrioza, also known as AMX0035, has been approved by Health Canada subject to conditions, including…Read More

VALOR Biogen’s Tofersen trial: a look at the open label extension data

Tofersen, has been designed to work by stopping the production of abnormal SOD1 protein that…Read More

Eledon Announces Positive Topline Results from Phase 2a Trial of Tegoprubart

Topline results from the Phase 2a trial of Tegoprubart have been announced, showing the drug…Read More

FDA approves Oral Form of Radicava for the treatment of adults with MND

On May 12, the US Food and Drug Administration (FDA) granted approval to oral edaravone…Read More

Rapid Progress in ALS/MND: A Reflection of Advances in Neuromuscular Disorder Care

With a burst of activity in recent months, the pipeline of development for ALS/MND has…Read More

CRISPR- the magic behind gene editing in MND

If you are interested in learning more about CRISPR read this blog by MND Association…Read More

Wave Life Sciences announces interim results for the FOCUS-C9 clinical trial

Wave Life Sciences announces a positive update to the ongoing phase 1b/2a FOCUS-C9 Study which…Read More

Earlier dementia detection could change lives. Can this NZ study unlock the secret?

Signs of dementia can be treated if they’re found early enough, but early detection is…Read More

Silence is golden: A new clinical trial for FUS-ALS

Researchers at King’s College London led by New Zealander Professor Christopher Shaw, are the first…Read More

ALS-TDI & Google develop new ALS/MND symptom severity measurement tool

A new machine learning algorithm to measure ALS/MND symptom severity has been developed by Google…Read More

TDP-43 pathology: From noxious assembly to therapeutic removal

Dr Scotter and Dr Swanson from the University of Auckland in collaboration with researchers at…Read More

Early Access Program for Tofersen in SOD1-ALS

Biogen has expanded eligibility for its early access program (EAP) for the investigational therapy tofersen. …Read More

Identifying disease progression in MND

An international collaboration led by Flinders University identified a potential biomarker for ALS/MND, providing a…Read More

Detailed images of molecule associated with ALS could open door to therapies

Scientists at the Medical Research Council Laboratory for Molecular Biology in Cambridge, UK have determined…Read More

Trinity College researchers make breakthrough in understanding MND

Researchers at Trinity College Dublin, have found that MND has 4 distinct patterns of changes…Read More

Positive Phase 1 Results, Regulatory Progress Announced for 2 Therapeutics in ALS

Two investigational small molecule therapeutics have reported positive phase 1 clinical results, as well as…Read More